Studies
Long Term Cohort Analysis

HIV-NAT006

Study ID: HIV-NAT006
This is a long-term, post study cohort of HIV-infected patients who previously participated in HIV-NAT study protocols. Information collected from this cohort will provide further insights into the long-term safety and durability of various antiretroviral therapeutic approaches, efficacy of HIV viral load and CD4 cell counts as predictors of disease progression, mortality, resistance profiles, adherence, immune recovery syndrome, opportunistic infections or malignancies, incidence of lipodystrophy, other metabolic complications, cardiovascular, renal, hepatic, and endocrine function, skin, gastrointestinal system and urogenital tract problems and quality of life.
Status: Ongoing since May 2007. All patients are followed and monitored.
Target/Enrolled: Unlimited/1882

HIV-NAT015

Study ID: HIV-NAT015
This is a long-term follow-up study of safety and efficacy of antiretroviral therapy for HIV positive children who have previously participated in HIV-NAT study protocols.
Status: Ongoing since July 2003. All patients are followed and monitored
Target/Enrolled: Unlimited/378
Collaborator: Chitsanu Panchareon, David A. Cooper, Joep MA Lange
Site: Chulalongkorn Hospital

Bone Health and Vitamin D status in Thai HIV-1 Infected and Uninfected Adults (A substudy of TNT-HIV 003: Trends of morbidity and mortality among Thai HIV-infected and HIV-uninfected patients: a five-year prospective cohort study

Study ID: TNT003.1
This study will compare and assess the prevalence of osteopenia and vitamin D deficiency as well as effects of TDF on the patients' bone among HIV positive and negative patients.
Status: Ongoing. Closed to recruitment. Patients are followed and monitored.
Target/Enrolled: 237/237

Metabolic disease and bone health in HIV positive patients compared to HIV uninfected

Study ID: TNT-HIV003
This is a five-year prospective cohort study that investigates the trends of morbidity and mortality among Thai HIV-infected and HIV-uninfected patients. This study has one substudy, TNT-HIV 003.1, which assesses the bone health and vitamin D status in HIV-1 infected and uninfected adults.
Status: Started in Oct. 2010. Closed to recruitment. Patients are followed and monitored.
Target/Enrolled: Group 1 (HIV infected):408/299; Group 2 (HIV uninfected):408/295
Collaborator: Peter Reiss and Ferdinand Wit, Amsterdam Institute for Global Health and Development (AIGHD)
Site Pls: The Thai Red Cross AIDS Research Centre: Praphan Phanuphak; Bamrasnaradura Infectious Disease Institute: Wisit Prasithisirikul; Queen Savang Vadhana Memorial Hospital: Tanate Jadwattanakul
Site: The Thai Red Cross AIDS Research Centre: Praphan Phanuphak; Bamrasnaradura Infectious Disease Institute: Wisit Prasithisirikul; Queen Savang Vadhana Memorial Hospital: Tanate Jadwattanakul

The Thai HIV Disease Progression: An Observational Database

Study ID: HIV-NAT153/The Progress (Adult cohort)
This is a multicenter, observational prospective cohort study – open cohort that will study the HIV disease progression in HIV-infected Thai Adult.
Status: Closed 2015
Target/Enrolled: 7000/5622
Collaborator: Department Disease Control (DDC), Thailand
Site Pls: Bamrasnaradura Infectious Disease Institute: Wisit Prasithsirikul; San Patong Hospital: Virat Klinbuayaem
Site: Bamrasnaradura Infectious Disease Institute, San Patong Hospital and HIV-NAT

The Thai Pediatric HIV Disease Progression: An Observational Database

Study ID: HIV-NAT154/Pediatric Progress
The objective of this cohort is to describe the multicenter cohort of HIV-infected children in Thailand
Status: Closed 2015
Target/Enrolled: 1,500 HIV-infected children from 4 sites/1348; HIV-NAT: 500/303
Collaborator: Office of the National Research Council of Thailand, and Bamrasnaradura Infectious Diseases Institute, Nonthaburi
Site: Chiangrai Prachanukroh Hospital, Sanpatong Hospital, Faculty of Medicine, Siriraj Hospital, Mahidol University

The Treat Asia HIV Observational Database

Study ID: HIV-NAT048/TAHOD
This study collects observational data on HIV-infected patients from a number of sites in several Asian countries. The information gathered will help develop more effective research and treatment programs for people living with HIV/AIDS in the region.
Status: Opened on January 15, 2008. Ongoing. All patients are followed and monitored.
Target/Enrolled: Unlimited/352 HIV-NAT&TRC-ARC
Collaborator: Mana Khongpatanayothin and David A. Cooper; Chulalongkorn Hospital
Site: Chulalongkorn Hospital
Coordinating Center: The Kirby Institute for Infection and Immunity in Society, Sydney, Australia

TREAT Asia Pediatric HIV Observational Database

Study ID: HIV-NAT080/TApHOD
This study is an HIV pediatric HIV observational database collecting HIV clinical data from 6 countries located in the Asia-Pacific region. This information will be used to develop more effective research and treatment programs for people with HIV/AIDS in the region.
Status: Opened May 3, 2007. Ongoing. All patients are followed and monitored
Target/Enrolled: Unlimited/340 HIV-NAT
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