{"id":1808,"date":"2018-12-31T00:00:42","date_gmt":"2018-12-30T17:00:42","guid":{"rendered":"https:\/\/www.hivnat.org\/en\/?p=1808"},"modified":"2018-12-31T00:00:42","modified_gmt":"2018-12-30T17:00:42","slug":"cross-sectional-study-examining-the-prevalence-rate-and-determinants-of-frailty-in-the-hiv-positive-and-negative-thai-populations","status":"publish","type":"post","link":"https:\/\/www.hivnat.org\/en\/studies\/1808\/","title":{"rendered":"Cross-sectional study examining the prevalence rate and determinants of frailty in the HIV positive and negative Thai populations"},"content":{"rendered":"\n\t\t\t\t\n<p><strong>Project no.: <\/strong>HIV-NAT 232\/Frailty<\/p>\n\n\n\n<p>This is a cross-sectional study\nexamining the prevalence rate and determinants of frailty in the HIV positive\nand negative Thai populations<\/p>\n\n\n\n<p><strong>Results: <\/strong>A total of 324 HIV-positive and 131 HIV-negative controls aged &gt; 50 years were enrolled, 37.0% were females with a mean (SD) age of 56.0 (5.5) years and 32.6% were females with a mean (SD) age of 58.3 (5.8) years, respectively. HIV-positive subjects were on cART for a mean duration of 15.2 (4.5) years. Comorbidity prevalence in the HIV-positive group was: hypertension 36.7%, hyperlipidemia 34.0%, diabetes 15.1%, renal dysfunction 7.1%, hepatitis B 13.0%, and hepatitis C 4.4%, and cardiovascular disease 2.2%. Pre-frailty (62.0% vs. 46.2%) (P \u2264 0.005), and frailty (6.5% vs. 1.5%) were more prevalent in the HIV-positive group as was the case for each of the five domains. In multivariable analysis, factors associated with frailty were HIV status (OR 2.04, 95%CI 1.24-3.35, P &lt; 0.005) and female gender (OR 3.97, 95% CI 2.36-6.67, P &lt; 0.001). In the analysis of HIV-positive subjects only, of the sociodemographic, HIV-related, and comorbidity-related covariates, only hypertension (OR 2.40, 95% CI 1.32-4.35, P &lt; 0.004) was significantly associated with frailty.<\/p>\n\n\n\n<p>(Source: Do T, et al., Frailty is Associated\nwith HIV and Female Sex in Asians 0ver 50. Abstract # TUPEB134. Presented at\nAIDS Conference 2018)<\/p>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\t\t\t\tThis is a cross-sectional study examining the prevalence rate and determinants of frailty in the HIV positive and negative Thai populations\t\t<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[24],"tags":[],"class_list":["post-1808","post","type-post","status-publish","format-standard","hentry","category-studies"],"_links":{"self":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/1808","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/comments?post=1808"}],"version-history":[{"count":0,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/1808\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/media?parent=1808"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/categories?post=1808"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/tags?post=1808"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}