{"id":1998,"date":"2017-12-31T00:00:59","date_gmt":"2017-12-30T17:00:59","guid":{"rendered":"https:\/\/www.hivnat.org\/en\/?p=1998"},"modified":"2022-03-30T09:56:17","modified_gmt":"2022-03-30T02:56:17","slug":"a-phase-ii-iii-multicenter-open-label-multicohort-two-part-study-evaluating-pharmacokinetics-pk-safety-and-efficacy-of-cobicistat-boosted-atazanavir-atv-co-or-cobicistat-boosted-darunavir-d","status":"publish","type":"post","link":"https:\/\/www.hivnat.org\/en\/studies\/1998\/","title":{"rendered":"A phase 2\/3, multicenter, open-label, multicohort, two-part study evaluating Pharmacokinetics (PK), safety, and efficacy of cobicistat-boosted Atazanavir (ATV\/co) or cobicistat-boosted Darunavir (DRV\/co), administered with Background Regimen (BR) in HIV-1 infected, treatment-experienced, virologically suppressed pediatric subjects"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">This study will evaluate the steady-state pharmacokinetics (PK) and\nconfirm the dose of cobicistat-boosted atazanavir (ATV\/co) or\ncobicistat-boosted darunavir (DRV\/co) in HIV-1 infected antiretroviral\ntreatment-experienced pediatric participants between the ages of 3 months to\n&lt; 18 years of age.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It will also evaluate the safety, tolerability, and efficacy of ATV\/co\nor DRV\/co each co-administered with a background regimen (BR) through 48 weeks\nand during long-term treatment (total of 5 years).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\t\t\t\tThis study will evaluate the steady-state pharmacokinetics (PK) and confirm the dose of cobicistat-boosted atazanavir (ATV\/co) or cobicistat-boosted darunavir (DRV\/co) in HIV-1 infected antiretroviral treatment-experienced pediatric participants between the ages of 3 months to < 18 years of age.\t\t\n<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[24],"tags":[],"class_list":["post-1998","post","type-post","status-publish","format-standard","hentry","category-studies"],"_links":{"self":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/1998","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/comments?post=1998"}],"version-history":[{"count":2,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/1998\/revisions"}],"predecessor-version":[{"id":3324,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/1998\/revisions\/3324"}],"wp:attachment":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/media?parent=1998"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/categories?post=1998"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/tags?post=1998"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}