{"id":2257,"date":"2014-12-31T00:00:46","date_gmt":"2014-12-30T17:00:46","guid":{"rendered":"https:\/\/www.hivnat.org\/en\/?p=2257"},"modified":"2014-12-31T00:00:46","modified_gmt":"2014-12-30T17:00:46","slug":"characteristics-and-clinical-significances-of-hepatitis-c-genotype-in-hiv-and-hepatitis-c-co-infected-thai-patients","status":"publish","type":"post","link":"https:\/\/www.hivnat.org\/en\/studies\/2257\/","title":{"rendered":"Characteristics and clinical significances of hepatitis C genotype in HIV- and hepatitis C co-infected Thai patients"},"content":{"rendered":"\n\t\t\t\t\n<p class=\"wp-block-paragraph\"><strong>Project no.:<\/strong> HIV-NAT 125\/HCV<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This is a cross-sectional study that will assess the HCV genotype and gene interleukin 28 (IL-28) in Thai HIV\/HCV co-infected patients.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Results: <\/strong>HCV genotype 3 (47%) is predominant circulating HCV genotypes in our HIV\/HCV co-infection and HCV mono infection, following by genotype 1 (34%) and genotype 6 (18%). High prevalence of HCV genotype 6 was observed (13% HIV\/HCV and 18% HCV mono). HCV genotype 6 tended to have higher HCV RNA but lesser liver fibrosis compared to HCV genotype 1 and 3. Approximately, 91% of our patients have favorable IL-28B gene. Factors associated with moderate to severe liver fibrosis in our HCV patients were HIV-coinfection, HCV genotype 3 and Fib-4 > 1.45<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Presentation:<\/strong> Avihingsanon A, Mek-A-nantawat W, Apornpong T, Akkarathamrongsin S, Ubolyam S, Chomhong P, Tangkitvanich P. Distribution of HCV genotype and Single Nucleotide Polymorphisms (SNPs) of IL-28B gene in HIV\/HCV coinfected Thai Populations. [Poster # P132] presented at the International Congress on Drug Therapy in HIV. Glasgow, Glasgow, UK. 11-15 November 2012.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Publication:<\/strong> J Gastroenterol Hepatol. 2014 Sep;29(9):1706-14.&nbsp;<\/p>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\t\t\t\tThis is a cross-sectional study that will assess the HCV genotype and gene interleukin 28 (IL-28) in Thai HIV\/HCV co-infected patients.\t\t<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[24],"tags":[],"class_list":["post-2257","post","type-post","status-publish","format-standard","hentry","category-studies"],"_links":{"self":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/2257","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/comments?post=2257"}],"version-history":[{"count":0,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/2257\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/media?parent=2257"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/categories?post=2257"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/tags?post=2257"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}