{"id":2354,"date":"2013-12-31T00:00:14","date_gmt":"2013-12-30T17:00:14","guid":{"rendered":"https:\/\/www.hivnat.org\/en\/?p=2354"},"modified":"2022-03-30T10:08:06","modified_gmt":"2022-03-30T03:08:06","slug":"a-phase-iii-two-part-study-to-evaluate-the-efficacy-of-tenofovir-alafenamide-versus-placebo-added-to-a-failing-regimen-followed-by-treatment-with-elvitegravir-cobicistat-emtricitabine-tenofovir-alafe","status":"publish","type":"post","link":"https:\/\/www.hivnat.org\/en\/studies\/2354\/","title":{"rendered":"A phase 3, two-part study to evaluate the efficacy of Tenofovir Alafenamide versus placebo added to a failing regimen followed by treatment with Elvitegravir\/Cobicistat\/Emtricitabine\/Tenofovir Alafenamide in HIV-1 positive, antiretroviral treatment-experienced adults"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Project no.: <\/strong>HIV-NAT 200\/GS-US-292-0117<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This study is divided into 2 parts. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Part 1 is a randomized, double-blind comparison of the addition of tenofovir alafenamide (TAF) or placebo to the antiviral (ARV) regimens of HIV-positive adults who are failing their current ARV regimen. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In Part 2, after a 14-day washout period all participants will receive open-label elvitegravir\/cobicistat\/emtricitabine\/tenofovir alafenamide single-tablet regimen (E\/C\/F\/TAF STR) and be followed for at least 48 weeks.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\t\t\t\tThis study is divided into 2 parts. Part 1 is a randomized, double-blind comparison of the addition of tenofovir alafenamide (TAF) or placebo to the antiviral (ARV) regimens of HIV-positive adults who are failing their current ARV regimen. \t\t<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[24],"tags":[],"class_list":["post-2354","post","type-post","status-publish","format-standard","hentry","category-studies"],"_links":{"self":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/2354","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/comments?post=2354"}],"version-history":[{"count":1,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/2354\/revisions"}],"predecessor-version":[{"id":3355,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/2354\/revisions\/3355"}],"wp:attachment":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/media?parent=2354"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/categories?post=2354"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/tags?post=2354"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}