{"id":3383,"date":"2022-03-30T10:19:42","date_gmt":"2022-03-30T03:19:42","guid":{"rendered":"https:\/\/www.hivnat.org\/en\/?p=3383"},"modified":"2022-03-30T10:19:44","modified_gmt":"2022-03-30T03:19:44","slug":"implementation-of-latent-tuberculosis-infection-screening-and-novel-treatment-one-month-rifapentine-plus-isoniazid-in-end-stage-renal-disease-patients-and-on-renal-replacement-therapy","status":"publish","type":"post","link":"https:\/\/www.hivnat.org\/en\/studies\/3383\/","title":{"rendered":"Implementation of latent tuberculosis infection screening and novel treatment one-month Rifapentine plus Isoniazid in end-stage renal disease patients and on renal replacement therapy"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">This is a collaborate study done with the Renal Division, Department of Medicine, Faculty of Medicine, Chulalongkorn University. This study is a single-center, prospective cohort study conducted at the Faculty of Medicine, Chulalongkorn University. 60-90 ESRD patients and on renal replacement therapy will be enrolled into this study. This study will assess the following: the study pharmacokinetic parameters of Rifapentine in ESRD patients and on renal replacement therapy; study safety and tolerability of one-month Rifapentine plus Isoniazid regimen in ESRD patients receiving renal replacement therapy; study adherence rates; study treatment discontinuation rate from adverse events; the prevalence of LTBI in patients preparing for kidney transplantation; factors associated with LTBI in ESRD patients and on renal replacement therapy; TB incidences among participants receiving the regimen; TB incidences among participants after transplantation; investigate patterns of antibiotic resistance of <em>Mycobacterium tuberculosis<\/em> in failed participants, and all-cause mortality rates among participants during the 3-year follow up period and after transplantation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This is a collaborate study done with the Renal Division, Department of Medicine, Faculty of Medicine, Chulalongkorn University. This study is a single-center, prospective cohort study conducted at the Faculty&hellip; <\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[24],"tags":[],"class_list":["post-3383","post","type-post","status-publish","format-standard","hentry","category-studies"],"_links":{"self":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/3383","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/comments?post=3383"}],"version-history":[{"count":1,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/3383\/revisions"}],"predecessor-version":[{"id":3384,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/3383\/revisions\/3384"}],"wp:attachment":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/media?parent=3383"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/categories?post=3383"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/tags?post=3383"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}