{"id":4358,"date":"2024-09-05T10:02:48","date_gmt":"2024-09-05T03:02:48","guid":{"rendered":"https:\/\/www.hivnat.org\/en\/?p=4358"},"modified":"2024-09-05T10:02:50","modified_gmt":"2024-09-05T03:02:50","slug":"giving-standardized-estradiol-therapy-in-transgender-women-to-research-interactions-with-hiv-therapy-the-get-it-right-study-a5403","status":"publish","type":"post","link":"https:\/\/www.hivnat.org\/en\/studies\/4358\/","title":{"rendered":"Giving Standardized Estradiol Therapy In Transgender Women to Research Interactions with HIV Therapy: the GET IT RIgHT Study (A5403)"},"content":{"rendered":"\n<p>The study is a phase IIb, 48-week, open-label, non-randomized, three-group trial of adult transgender women (TW) and other individuals identifying as<br>female or transfeminine but with male sex assigned at birth (henceforth referred to in aggregate as TW) living with human immunodeficiency virus-1 (HIV-1).<br>The primary objectives of the study are to 1)<br>assess whether TW continue to achieve therapeutic concentrations of ART while receiving FHT for 48 weeks, and 2) assess whether serum estradiol concentrations on FHT (across a range of estradiol doses) vary between boosted and unboosted ART regimens.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The study is a phase IIb, 48-week, open-label, non-randomized, three-group trial of adult transgender women (TW) and other individuals identifying asfemale or transfeminine but with male sex assigned at birth&hellip; <\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[24],"tags":[],"class_list":["post-4358","post","type-post","status-publish","format-standard","hentry","category-studies"],"_links":{"self":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/4358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/comments?post=4358"}],"version-history":[{"count":1,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/4358\/revisions"}],"predecessor-version":[{"id":4359,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/posts\/4358\/revisions\/4359"}],"wp:attachment":[{"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/media?parent=4358"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/categories?post=4358"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hivnat.org\/en\/wp-json\/wp\/v2\/tags?post=4358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}