To explore the antiretroviral efficacy and tolerability of therapy with d4T/ddI in patients pretreated with AZT/3TC…
Category: Studies
A randomized, open-label, comparative trial of AZT/3TC/ddI om antiretroviral naïve HIV-1 infected in Thai patients
An in vitro study comparing the ability of ten different three-drug combinations to prevent HIV-induced cytopathic…
A randomized, open-label follow-up study of protocol HIV-NAT 001 to explore the antiretroviral efficacy and tolerability of switching to therapy with d4T/ddI/Saquinavir soft gel capsules versus Combivir (AZT/3TC)/Saquinavir soft gel capsules in an HIV-infected Thai population pretreated with AZT and ddC for at least 48 weeks
Study Endpoint: Primary: Percentage of patients achieving sustained undetectable HIV-1 RNA in plasma (Amplicor HIV-1 Moniror)…
A phase 2 randomized, four arm, open-label, comparative trial to evaluate the efficacy and tolerance of combination antiretroviral therapy with ddI + d4T alone or in combination with either nevirapine, hydroxyurea or both nevirapine and hydroxyurea for the treatment of HIV-1 infection in a Thai study population
Hydroxyurea (HU) blocks DNA synthesis by inhibitoion of the cellular enzyme ribonucleotide reductase. It has been…
A phase 3, open-label, follow-up study to protocol HIV-NAT 002.1 to explore the durability of the antiretroviral efficacy and durability of ddI/d4T and AZT/3TC in a population originally treated with ddI/d4T, and explore the efficacy of adding hydroxyurea to failing therapy with two nucleosides
To determine durability of the virological and immunological responses of participants on study 002.1 who were…
A study of the safety, tolerance and pharmacokinetics of Nelfinavir co-administered with Stavudine (d4T) and Didanosine (ddI) in HIV-exposed infants
The pediatric oral powder formulation of Nelfinavir has been studied in small groups of HIV-infected children
