Oral Islatravir (MK-8591) Once-Monthly as Preexposure Prophylaxis (PrEP) in Men and Transgender Women Who Have Sex With Men and Are at High Risk for HIV-1 Infection (MK-8591-024)

The main purpose of the study is to evaluate the efficacy and safety of oral Islatravir…

A phase 1/2, dose-finding study to evaluate safety, tolerability, and immunogenicity of the ChulaCov19 vaccine in Healthy Adults

Brief summary: This study will be conducted as a combined phase 1/2 study in healthy participants.…

A phase 2/3, randomized, double-blind, double-dummy, placebo controlled study to evaluate the safety and efficacy of 2 regimens of orally administered PF 07321332/Ritonavir in preventing symptomatic SARS-COV-2 infection in adult household contacts of an individual with symptomatic COVID-19

Brief summary: The purpose of this study is to evaluate the efficacy and safety of PF-07321332/ritonavir…

An interventional efficacy and safety, phase 2/3, double-blind, 2-arm study to investigate orally administered PF-07321332/Ritonavir compared with placebo in nonhospitalized symptomatic adult participants with COVID-19 who are at increased risk of progressing to severe illness

Brief summary: The purpose of this study is to determine whether PF-07321332/ritonavir is safe and effective…

An interventional efficacy and safety, phase 2/3, double-blind, 2-arm study to investigate orally administered PF-07321332/Ritonavir compared with placebo in nonhospitalized symptomatic adult participants with COVID-19 who are at low risk of progressing to severe illness

Brief summary: The primary hypothesis to be tested is whether or not there is a difference…

Immunogenicity of COVID-19 vaccines in people living with HIV

An International Multicenter, Adaptive, Randomized Double-Blind, Placebo-Controlled Trial of the Safety, Tolerability and Efficacy of Anti-Coronavirus Hyperimmune Intravenous Immunoglobulin for the Treatment of Adult Hospitalized Patients at Onset of Clinical Progression of COVID-19

Brief Summary: This protocol will serve as a platform for assessing treatments for adult patients hospitalized…

An International Observational Study to Characterize Adults Who Are Hospitalized With Influenza or Other Targeted Respiratory Viruses

Following the sudden and unexpected emergence of influenza A(H1N1)pdm09 (2009 H1N1) virus, this observational study was…

A Single-arm Study to Evaluate the Feasibility and Efficacy of a Minimal Monitoring Strategy to Deliver Pan-genotypic Ribavirin-free HCV Therapy to HCV Infected Populations who are HCV Treatment Naïve with Evidence of Active HCV Infection: The MINMON Study

HBV and HCV in prison

This study is part of the LTBI in prison study. This study is the secondary objective.…

Multicenter clinical performance evaluation of the Molbio Diagnostics Truenat™ HCV RNA assay

This is a new diagnostic test to detect HCV with shorter turnaround time. This study will…

Test and Treat HIV and Viral Hepatitis for People Who Use Drugs and Their Partners in Thailand: The C-Free Study

This is a multi-center cohort study with a nested, open-label clinical trial. This study will: Assess…

Program to help develop and propel HCV treatment

This study offers HCV treatment for all HCV infected population.

B-enchancement of HBV vaccination in persons living with HIV (Bee-HIVe): Evaluation of HEPLISAV-B

The purpose of this study is to evaluate response to and safety of the HBV vaccine…

A Prospective, Multi-Centre Study (B-Sure) to Evaluate Long-Term Durability of Sustained Virologic Response in Chronic Hepatitis B Participants With and Without Nucleos(t)ide Therapy Who Have Received and Responded to GSK3228836 in a Previous Treatment Study

This is a long-term follow-up study to assess durability of efficacy, as measured by SVR, in…