The study is a phase 3, randomized, placebo-controlled, double-blind trial of tecovirimat for the treatment of…
Category: Studies
A Phase 2, Randomized, Adaptive, Dose-Ranging, Open-Label Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (RAD-TB) (A5409)
The study is an adaptive Phase 2 randomized, controlled, open-label, dose-ranging, platform protocol to evaluate the…
A Phase 3, multicenter, randomized, double-blind, 24-week study of the clinical and antiviral effect of S-217622 compared with placebo in non-hospitalized participants with COVID-19 (A5407)
The study is a Phase 3, multicenter, randomized,double-blind, placebo-controlled trial to evaluate the safety and efficacy…
Pharmacokinetics and Safety of Double-dose Dolutegravir When Used with Rifapentinefor HIV-associated Tuberculosis (A5406)
The study is an open-label, phase II, single-arm, multicenter pharmacokinetic (PK) study to investigate the effect…
Giving Standardized Estradiol Therapy In Transgender Women to Research Interactions with HIV Therapy: the GET IT RIgHT Study (A5403)
The study is a phase IIb, 48-week, open-label, non-randomized, three-group trial of adult transgender women (TW)…
A Phase 2a/2b Randomized, Placebo-Controlled Study Evaluating Safety, Immunogenicity, and Therapeutic Efficacy of ID93 + GLA-SE Vaccination in Participants with Rifampicin-Susceptible Pulmonary TB ( A5397/HVTN 603)
The study is a double-blinded, placebo-controlled study with a Phase 2a and a Phase 2b component…
Safety, Tolerability, and Impact of Oral TLR8 Agonist Selgantolimod on HBsAg in Participantswith Both Chronic Hepatitis B and HIV (A5394)
The study is a phase II, randomized, double-blind, placebo-controlled clinical trial to assess the safety, tolerability,…
Decay of HIV-1 Reservoirs: The ACTG HIV Reservoirs Cohort (AHRC) Study (A5321)
The study is a study of longitudinal changes in HIV-1 reservoirs among participants with HIV-1 who…
A Phase II, Prospective, Randomized, Multicenter Trial to Evaluate the Efficacy and Safety/Tolerability of Two Linezolid Dosing Strategies in Combination with a Short Course Regimen for the Treatment of Drug-Resistant Pulmonary Tuberculosis (A5356)
The study is a phase II, prospective, randomized, two-arm, open-label, multicenter clinical trial to evaluate the…
Oral Islatravir (MK-8591) Once-Monthly as Preexposure Prophylaxis (PrEP) in Men and Transgender Women Who Have Sex With Men and Are at High Risk for HIV-1 Infection (MK-8591-024)
The main purpose of the study is to evaluate the efficacy and safety of oral Islatravir…
A phase 1/2, dose-finding study to evaluate safety, tolerability, and immunogenicity of the ChulaCov19 vaccine in Healthy Adults
Brief summary: This study will be conducted as a combined phase 1/2 study in healthy participants.…
A phase 2/3, randomized, double-blind, double-dummy, placebo controlled study to evaluate the safety and efficacy of 2 regimens of orally administered PF 07321332/Ritonavir in preventing symptomatic SARS-COV-2 infection in adult household contacts of an individual with symptomatic COVID-19
Brief summary: The purpose of this study is to evaluate the efficacy and safety of PF-07321332/ritonavir…
An interventional efficacy and safety, phase 2/3, double-blind, 2-arm study to investigate orally administered PF-07321332/Ritonavir compared with placebo in nonhospitalized symptomatic adult participants with COVID-19 who are at increased risk of progressing to severe illness
Brief summary: The purpose of this study is to determine whether PF-07321332/ritonavir is safe and effective…
An interventional efficacy and safety, phase 2/3, double-blind, 2-arm study to investigate orally administered PF-07321332/Ritonavir compared with placebo in nonhospitalized symptomatic adult participants with COVID-19 who are at low risk of progressing to severe illness
Brief summary: The primary hypothesis to be tested is whether or not there is a difference…
