Project no.: HIV-NAT 139
The objectives of this study is to compare the prevalence of HPV infection among perinatally HIV-infected adolescents, behaviorally HIV-infected adolescents, and HIV-negative adolescents, and compare the prevalence of intraepithelial neoplasia and presence of E6/E7 biomarker at cervical and anal sites among perinatally HIV-infected adolescents, behaviorally HIV-infected adolescents, and HIV-negative adolescents.
Results: At least one-third of perinatally and behaviorally HIV-infected adolescents had abnormal cytology and at least half had HPV infection and E6/E7 oncogenic mRNA. HIV positive adolescents need access to preventative HPV immunization and routine monitoring for pre-cancerous and cancerous changes.
Presentation: Ananworanich J, Prasitsuebsai W, Kerr SJ, Phasomsap C, Pankam T, Rodbamrung P, Teeratakulpisarn N, Petdachai W, Sohn, Phanuphak N on behalf of the HIV-NAT 139 Study Group. Prevalence of Cervical and Anal HPV Infection and Intraepithelial Neoplasia Biomarkers in Perinatally and Behaviorally HIV-Infected Compared to HIV-Negative Adolescents. [Poster # S-147] presented at the 19th Conference on Retrovirus and Opportunities Infections (CROI 2012). Seattle, WA USA. March 5-8, 2012.
