Maintenance of switching from Protease Inhibitor/Ritonavir to generic single tablet regimen of Tenofovir Alafenamide/Emtricitibine/Dolutegravir in virologically suppressed HIV-infected adults

The fundamental principle of regimen switching is to maintain viral suppression without jeopardizing future treatment options.

An international observational study to characterize adults who are hospitalized with complications of influenza A – pandemic H1N1 (H1N1v)

The purpose of this observational study is to describe the characteristics and outcomes over a 60-day…

A phase IIIb, randomized, open-label study of the safety and efficacy of Dolutegravir/Abacavir/Lamivudine once daily compared to Atazanavir and Ritonavir plus Tenofovir/Emtricitabine once daily in HIV-1 infected antiretroviral therapy naïve women

This study is designed to demonstrate the non-inferior antiviral activity of DTG/ABC/3TC fixed dose combination (FDC)…

Treatment outcome of children with HIV infection treated with highly active antiretroviral therapy (HAART)

This is a long-term follow-up study of safety and efficacy of antiretroviral therapy for HIV positive…

Management Using the Latest Technologies In resource-limited settings to Optimize Combination Therapy After Viral Failure (MULTI-OCTAVE)

This is a randomized, open labelled, multicentered international study that will assess the efficacy, safety and…

A phase III multicenter, double-blind, randomized, active comparator-controlled clinical trial to evaluate the safety and efficacy of MK-1439A once-daily versus ATRIPLA once-daily in treatment-naïve HIV-1 infected subjects

This study will compare the antiretroviral activity of MK-1439A, a single-tablet, once-daily (q.d.) fixed-dose combination (FDC)…

A pilot study of the pharmacokinetics and safety of Rifabutin 150 mg once daily versus Rifabutin 150 mg thrice weekly with Lopinavir/Ritonavir based HAART in HIV/TB co-infected patients

This is a pilot, randomized, open-label, 2-arm per group, parallel, phase II study that will describe…

A phase II intensification study of BIT225, a HIV-1 Vpu inhibitor, in HIV-1 infected individual initiating combination antiretroviral therapy (cART)

This is a phase 2, intensification study of BIT225, a HIV-1 Vpu inhibitor, in HIV-1 Infected…

Collection of key tuberculosis (TB) variables in antiretroviral therapy (ART) programs within the international epidemiologic databases to evaluate AIDS (IeDEA) consortium: Diagnostics, treatment and risk factors for incident TB

The overall goal is to collect, retrospectively and prospectively, key TB variables in ART programs within…

Open label phase II/III, multicenter, trial to assess the efficacy, safety, tolerance, and pharmacokinetics of sofosbuvir plus ravidasvir in HCV (+/- HIV) chronically infected adults with no or compensated cirrhosis in Thailand and Malaysia

This is an open label phase II/III, multicenter, trial to assess the efficacy, safety, tolerance, and…