Pharmacokinetics of low dose Raltegravir

Project no.: HIV-NAT 127/Raltegravir study

This study will compare the pharmacokinetics of raltegravir at 400 mg daily and 800 mg daily versus the standard 400 mg raltegravir taken twice daily among HIV-infected patients on ART and have HIV viral load less than 50 copies/ml.

Publications: Pharmacokinetics of and short-term virologic response to low-dose 400-milligram once-daily raltegravir maintenance therapy. Antimicrob Agents Chemother. 2012 Apr;56(4):1892-8. doi: 10.1128/AAC.05694-11.